ABSTRACT
Nanobiomaterials were used as nanocarriers for drug delivery or as enhancement factors for sensitivity or selectivity in point-of-care devices. Nanobiomaterials were incorporated in the design of biosensors in order to increase sensitivity, or for multiplexing. When micro fluidic devices are associated the biosensors, they may have a potential use in clinical analysis. Heating of organs and tissues by placing multifunctional nanomaterials at tumor sites is emerging as an art of tumor treatment by "nanothermal therapy" and it is applicable for all types of nanobiomaterials. Biological and synthetic polymers were used for the development of polymeric nanobiomaterials. Polysachharides such as alginate, chitosan, hyaluronic acid and their derivatives were used as biological polymers besides some proteins. Cancer biomarkers, like any other biomarker, are generally defined as "a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention".
