ABSTRACT
This chapter shows endophytic fungus Aspergillus niger that was isolated from leaves of Ficus panda for the synthesis of silver nanoparticles and to study the antibacterial activity against clinical human pathogenic microbial strains. The Ficus panda is from the family Moraceae and needs more light to have a vigorous growth. Different types of nanomaterials like copper, zinc, titanium, magnesium, gold alginate and silver have come up but silver nanoparticles have proved to be most effective because of antimicrobial efficacy against bacteria, viruses and other eukaryotic micro-organisms. Silver nanoparticles are used as drug disinfectant and have some risks as the exposure to silver can cause agyrosis and argyria also; and are toxic to mammalian cells. The first evidence of bacteria synthesizing silver nanoparticles was established using the Pseudomonas stutzeri strain that was isolated from silver mine. Nanoparticles showed significant antibacterial activity against Enterococcus sp., E. coli, Staphylococcus albus and Klebsiella pneumonia.
