ABSTRACT
The review is devoted to the results of our studies on the synthesis and modification of 2,3-secotriterpene compounds. The original 2,3-secotri- terpenoids were synthesized by Beckmann fragmentation of the A-ring of available derivatives of betulin (betulonic acid, its methyl ester and allobetulone). Directed chemical modification of the initial 2,3-secotriter- penoids has resulted in a wide spectrum of mono- and bi-functionalization products as well as products of heterocyclization and recyclization of the A-ring. Compounds with high antiviral and cytotoxic activity among the obtained products were found.
