ABSTRACT
Since several decades, epidemiological and cases studies have pointed out excess of developmental anomalies and imprinting disorders following ART suggesting that ART techniques/or infertility are associated with potential epigenetic risks. As developed in this review, one important procedure with regard to possible epigenetic alterations is ovarian stimulation. That may disrupt the acquisition of imprints which occurs specifically during this period. Moreover, induced ovarian stimulation may also modify the physiological environment of the uterus and the implantation. Even though these issues have been mostly highlighted in animals, they should encourage decreasing doses of exogeneous hormones as much as possible.
