ABSTRACT
Digital micro¦uidics is an emerging technology that provides ¦uid-handling capability on a chip [1-3]. By reducing the rate of sample and reagent consumption, digital micro¦uidics lab-on-chip enables onchip immunoassays, point-of-care clinical diagnostics, and high-throughput DNA sequencing. Bioassay protocols are run on a lab-on-chip through the manipulation of discrete droplets of nanoliter volume under clock control on a 2D electrode array of electrodes (“unit cells”). A unit cell in the array includes a pair of electrodes that acts as two parallel plates. ¡e bottom plate contains a patterned array of individually controlled electrodes, and the top plate is coated with a continuous ground electrode. A droplet rests on a hydrophobic surface over an electrode, as shown in Figure 27.1 [4].
