ABSTRACT
This chapter provides the latest information about the occurrence of Transformation products (TPs) of different therapeutic classes of Pharmaceuticals and personal care products (PPCPs) in different environmental matrices with a geographical perspective, and summarizes the research activity worldwide. In general, the analytical approaches to the determination of the TPs were differentiated according to the reference standards and the prior information. Numerous studies have identified several TPs that stem from biotic or abiotic transformation processes that take place during the route that PPCPs follow in the environment. The most commonly detected TP is anhydroerythromycin, a TP of erythromycin, belonging in the class of macrolide antibiotics. The presence of antibiotics in the effluents of Hospital wastewater treatment plants or hospital wastewater treatment plants raises concerns since their presence in surface waters can contribute to an increase in bacterial species with antibiotic resistance.
