ABSTRACT
This chapter discusses applications of the chemical exchange satu-
ration transfer (CEST) technique in the context of hyperpolarized
(hp) exchanging xenon. For basic aspects of CEST with 1H magnetic
resonance imaging (MRI), the reader is referred to the previous
chapters of this book. Herein we focus on systems with hp xenon
that does not participate in covalent bonds (like in diaCEST) or
ligand coordination (paraCEST). Instead, it is a somewhat special
case of compartmental exchange as described in the proposed
nomenclature by van Zijl et al. [1].