ABSTRACT

Low-level laser therapy (LLLT), or phototherapy, has received a

lot of attention over the last decade. It has been used with great

success in a variety of in vitro and in vivo studies to promote wound healing. The exact mechanism of action is, however, not

well understood, and a number of theories exist. Increasingly, many

researchers have studied these underlyingmechanisms, and there is

growing evidence and a general consensus thatmitochondria are the

absorbing chromophore for red and near-infrared (NIR) laser light

(600-1000 nm). Photon energy is absorbed by the mitochondrial

chromophore and is converted to chemical energy and in doing so

stimulates the cell. This chapter focuses on the effects of LLLT on

cells and explores the influence on mitochondria and adenosine

triphosphate (ATP).