ABSTRACT

The development of the most potent formulation of whey protein and amino acid supplementation would potentially protect against the negative consequences of sarcopenic obesity in the elderly. The primary differences between essential amino acid meal replacement (EAAMR) and competitive meal replacement (CMR) were the total amount/ type of intact protein and the total amount and formulation of essential amino acids. In order to attenuate the acceleration of sarcopenia, the amount/type of protein and/or formulation of essential amino acids must be elucidated to promote efficacious caloric restriction-based weight loss in the elderly. Caloric restriction-induced weight loss that is often utilized to dampen the negative consequences of metabolic syndrome may be considered counterproductive when measured against weight loss-induced acceleration of sarcopenia. The chapter proposes that the changes in body composition would occur in conjunction with an increase in the skeletal muscle protein fractional synthetic rate to EAAMR compared to CMR.