ABSTRACT

The frequency of life threatening infections caused by pathogenic microorganisms has increased worldwide and is becoming an important cause of morbidity and mortality in immune compromised patients all over the world. Researchers for many decades have been trying to develop new broad-spectrum antibiotics for treating the infectious diseases caused by pathogenic microorganisms. Prolonged usage of these broad-spectrum antibiotics has led to the emergence of drug resistance. Different solvent extracts of S. oleoides showed poor antimicrobial activity against Gram negative bacteria and fungi as compare to Gram positive bacteria. Plants are important sources of biologically active natural products, which differ widely in terms of structure. They are the original source of a variety of compounds used by the pharmaceutical industry as medicines. Antimicrobial potential of two different Salvadoraspecies was evaluated and compared.