ABSTRACT
Significant research efforts are currently being focused on the development of innovative biomedical devices. In this regard, one of the most important challenges is the development of better biomaterials that combine the advantages of conventional natural and chemically synthesized materials while improving their properties. Recombinant proteins derived from natural proteins and genetically engineered polymers represent valuable alternatives due to their biocompatibility, biodegradability, non-toxic nature, and nonimmunogenic properties. Furthermore, such biomaterials are able to mimic different physiological tissue components and environments, a property that is much sought after in tissue regeneration, and are excellent candidates in controlled drug-or gene-release due to their multi-responsive behavior and their ability to carry therapeutic agents to specific targets.
