ABSTRACT
Over the last decade, the transarterial radioembolization with 90Y microspheres has emerged as a mainstream treatment modality for inoperable hepatic malignancies. Radioembolization with 90Y is a liver-directed therapy with the potential of delivering a high radiation dose directly to liver tumors in the form of localized β radiation, capable of sparing healthy tissue. Due to its long β particle range, 90Y allows for reasonably uniform irradiation of large tumors commonly expressing heterogeneous perfusion and hypoxia.
