ABSTRACT
Brain tumors are the most complicated and challenging in treatment. Life expectancy is very low, and conventional treatment such as chemotherapy is mostly ineffective due to the blood–brain barrier. This chapter introduces a new technology that is capable of imaging contrast and differentiating tissues in real time, based on indigenous tissue fluorophores’ response to optical excitation. It presents a robust method and system that brings innovation from multidisciplinary university research to undertake real-world topics. Detecting biochemical and molecular markers, which have been established in spectroscopic biomedical research, can be utilized not only to offer video-rate contrast imaging intraoperatively but also to provide a refuge in tissue screening limitations in brain repositories. Ultraviolet (UV) radiation is part of the electromagnetic spectrum, between the visible and x-ray regions, that spans from extreme UV at 10 nm to visible violet at 400 nm.
