ABSTRACT
The xMotif method, proposed by Murali and Kasif (2003) aims to find conserved gene expression motifs (xMotifs). An xMotif is defined as a subset of rows (genes) that is simultaneously conserved across a subset of the columns (conditions). Hence, xMotif can be seen as a bicluster. Note that although the xMotif method was developed for a gene expression application, it can be applied to any N ×M data matrix for which the identification of local patterns is of interest. The analysis presented in this chapter was conducted using the BiclustGUI package, which is a GUI consisting of several R packages for biclustering. An elaborate description of the package is given in Chapter 20.
