ABSTRACT
REVA Medical took a unique approach to fully integrate both a novel design and material in developing a sirolimus-eluting bioresorbable coronary scaffold. The REVA Scaffolds "family" includes two expansion designs, the Slide & Lock design as found in the ReZolve scaffold series and the Deformable design used in the Fantom scaffold series. The Deformable design expands in a similar manner to traditional metal drug-eluting stents and other bioresorbable scaffolds with a clinically significant expansion range of more than one millimeter from the nominal size. The Deformable Fantom platform is a single element device that contains a uniform thickness of approximately 125 μ across the full length of the scaffold. The structure of the polymer consists of a diester of iodinated desaminotyrosine along with common non-radiopaque biodegradable components. On absorption of water, the diester hydrolyzes to form two molecules of the iodinated desaminotyrosine along with other resorbable natural products.
