ABSTRACT
The ArterioSorb™ scaffold is manufactured using a patented die-drawing processing technique that results in improved radial strength. A number of different processing approaches have been developed to improve the material properties of polymers for BRSs including blow molding, dip coating, and annealing. This chapter provides a comparison of the ArterioSorb design with a number of other scaffolds. The construction of ArterioSorb ensures sufficient radial and longitudinal strength to enable the vessel to recover its natural shape while avoiding recoil and malapposition. Animal testing showed that the ArterioSorb markers were easily visible at each end of the scaffold leading to ease of implantation. The use of the novel die-drawing technique in the manufacture of ArterioSorb has resulted in the production of a scaffold with extremely promising results in terms of thinner strut thickness with greater radial strength. The scaffold design and geometry continues to be improved with on-going bench testing and further animal trials planned prior to a first-in-human trials.
