ABSTRACT

Dementia with Lewy bodies (DLB) is now the preferred term (McKeith et al., 1996) for a variety of clinical diagnoses including diuse Lewy body disease (DLBD) (Kosaka et al., 1984; Dickson et al., 1987; Lennox et al., 1989), Lewy body dementia (LBD) (Gibb et al., 1987), dementia associated with cortical Lewy bodies (DCLB) (Byrne et al., 1991), the Lewy body variant of Alzheimer’s disease (LBVAD) (Hansen et al., 1990; Förstl et al., 1993) and senile dementia of Lewy body type (SDLT) (Perry et al.,1990). Figure 61.1 provides a simple schematic of the relationship between the various Lewy body (LB) terminologies recommended currently, and consistency of usage is essential for a full understanding of the disorder. is chapter considers the evolution of diagnostic concepts and methods; the pathology and management of DLB are considered in subsequent chapters.