ABSTRACT
Nail signs associated with systemic disorders in children include nail symptoms that are specic for a disease and well known and also described in adults,1 i.e., the nails of the yellow nail syndrome, the periungual capillary changes seen in connective tissue disorders, and nail clubbing,2,3 and nail signs that are nonspecic and occasionally described as single-case reports or in case series not related to a specic disease (Table 11.1).1,4,5 The latter include symptoms such as nail fragility, Beau’s lines, and onychomadesis, which result from the damage to the nail matrix and can be seen in a high number of conditions, as well as nail changes that are very frequent and physiological in children such as toenail koilonychia. In all these cases, assessing the casual relationship with the systemic disease is not easy.
