ABSTRACT
Glomulin mutations cause glomuvenous malformations; lesions are small, bluish and painful. Capillary malformation is a cutaneous stain present at birth; it gradually darkens over the patient's lifetime and may develop cobblestoning. Glomuvenous malformation is an autosomal dominant condition resulting from a mutation in the glomulin gene; patients have multiple, small venous malformations with glomus cells that are painful. Arteriovenous malformation is a high-flow lesion that is complicated by bleeding, ulceration and pain. Interferon is occasionally utilised for some vascular tumours or lymphatic malformations, though not in infants, because of associated spastic diplegia. Ultrasound is often the initial radiographic examination following history and physical examination for the confirmation of a vascular anomaly; children do not require sedation. Interferon is occasionally utilised for some vascular tumours or lymphatic malformations, though not in infants, because of associated spastic diplegia. Embolisation is usually first-line treatment for problematic arteriovenous malformations. Sclerotherapy is typically first-line treatment for venous and lymphatic malformations.
