ABSTRACT
Children who present with acute abdominal pain and or a palpable abdominal mass can have ileocaecal intussusception from Peyer's patches in localised Burkitt's lymphoma. Unlike advanced Burkitt's lymphoma, surgical resection is the treatment of choice for these patients, who have an excellent prognosis with limited chemotherapy. Standard treatment for Hodgkin's lymphoma involves multiagent chemotherapy and radiation therapy. Although selected patients with low-risk disease may receive treatment that avoids radiation therapy, patients with advanced stage disease still require involved-field radiation to achieve high rates of cure. Chemotherapy for childhood lymphoma includes multiple drugs given in combination. Although acute side effects such as immunosuppression, nausea and alopecia are seen during treatment, long-term side effects are a significant problem for survivors, and patients require extensive follow-up after cure. The classical subtype of Hodgkin's lymphoma is characterised by Reed–Sternberg cells. The cells are unique in appearance because of their large size and characteristic 'owl's-eye' nucleus.
