ABSTRACT

Proton beams have been used for clinical radiotherapy due to the physical characteristics of protons and how they deposit dose. Most of the dose is delivered in the narrow Bragg peak which can be utilized to better target tumors while sparing dose to normal tissues. Clinical interest in using proton beams for radiotherapy started in the 1940s and numerous technological advancements to date have made proton therapy a widely utilized radiation technique. This chapter discusses the unique considerations for dosimetry of proton radiotherapy. The fundamentals of proton interactions with matter will be discussed as well as the various detectors and dosimetry protocols appropriate for proton beam measurements. Applications in the clinic will be covered with beam delivery techniques, quality assurance, and uncertainties associated with proton therapy.