ABSTRACT

Advances in the biocompatible arena of research have propelled researchers to exploit the inherent potential of ubiquitously distributed components called ‘lipid’. Lipids are well known to display a crucial role in the functionality and architecture of all living cells. Lipid-based entities can expediate the formation of solubilized phases from which absorption may occur. Owing to their biodegradable nature, small size, high versatility, and rapid metabolization, lipid nanoparticles are acting as interesting candidates for contrast agent and active component transport for delivery purposes. The chapter highlights the in-depth elucidation of two types of lipid nanoparticles, i.e. solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs), comprising the role of different preparation methods on their properties, showcasing advantages and disadvantages. The impact of surface modification on lipid nanostructures has been discussed elaborately with the objective of targeting these nanovehicles for drug delivery purposes.