ABSTRACT
The outreach of nanotechnology over the past 35 years is massive, making them ideal for various applications. This advancement is attributed to the improvement in the synthesis and characterization methods at the nanoscale. The convergence of nanotechnology and biotechnology has resulted in the rapid development of advanced biofunctionalized nanomaterials. Biofunctionalized nanomaterials are versatile materials incorporated with molecules of various biological origins such as proteins, peptides, DNA, and carbohydrates into nanoparticles, thus providing effective chemical, biosensing/bioimaging, photonic, and catalytic properties for various applications. The development in the fields of chemistry and biology has led to the advent of the synthesis and fabrication of designer biofunctionalized hybrid nanomaterials which are custom made for specific bioapplications. To follow the rapidly growing and developing area of advanced biofunctionalized nanomaterials, this chapter discusses various methodologies and the importance associated with each of the coupling strategies on the preparation of biofunctionalized nanomaterials.
