ABSTRACT
Though centipede venom resembles snake venom, there is no specific treatment for centipede envenomation in modern pharmaceuticals. The centipede venom produced by merocrine, which contains multi-antigenic components, is responsible for its effects. Centipede envenomation is not as simple as individuals take it and cannot be left as untreated. The invention of antivenomic active principles from plant sources are based on in vitro assays, like procoagulant, Phospholipase A2 and metalloprotease inhibition, proteolytic, fibrinolytic, defibrinogenolytic, haemolytic, inhibition of edema, inhibition of adenosine diphosphate, inhibition of induced platelet aggregation. Throughout the world, rural people are suffering from venomous bites and go for acute therapeutic treatment. Immediate hypersensitivity triggered by venom may have direct toxic effects, inducing local reaction and clinical symptoms. An immediate hypersensitivity reaction was observed among 48 human beings in Australia during the year 2000–2002 as pain and erythema and edema and itchiness.
