ABSTRACT
The strategy to design a suitable colloidal carrier is also dependent on other requirements, such as size, surface area, charge, media pH and media ionic strength. The performance of the agent relates to factors which determine the release profile of the agent from the colloidal assembly irrespective of whether the activity requires its release from the carrier. To a large extent, the ability to form a suitable assembly regarding efficiency and stability of agent-loading is dependent on the physicochemical properties of the agent and its mode of interaction with the molecules forming the carrier. Using a simplified approach, all relevant agent properties can be expressed through assortment into several classes. This classification is determined by two partition coefficients: oil/aqueous phase and octanol/aqueous phase. When using the same agent with various types of amphiphile-based carrier it becomes clear that the exact type of the colloidal assembly has a major impact on the performance of the agent associated with the assembly.
