The measurement of pressures in various portions of the reproductive tract is important in clinical monitoring and in basic research in reproductive biology. This chapter outlines pressure measurements have been used in other areas of obstetrics research by various investigators. It considers some of the other applications of pressure measurements in obstetrics. The indirect measurement is based on tonometry through the anterior abdominal wall using a tokodynamometer. Direct measurements of intrauterine pressure can be made either by means of a fluid-filled catheter coupling the amniotic cavity to an external pressure transducer, or through the use of a miniature semiconductor strain gauge pressure transducer placed in the amniotic cavity itself. Pressure measurements are also made in the nonpregnant uterus and oviduct using similar direct techniques; however the errors are often more serious. Pressure measurements are important both clinically and in basic research in obstetrics and gynaecology, as well as in reproductive biology in general.