ABSTRACT
Hitherto, the clinical physician has been reluctant to introduce fibrinolytic tests into his diagnostic arsenal. In view of recent developments, the question is due whether it is time to extend the set of assays measuring some aspects of fibrinolysis beyond the (seldom used) euglobulin lysis test and the (profusely used) conventional FDP-tests. In order to answer this question, clinical data regarding the role of t-PA in hemorrhage and thrombosis, especially those obtained with newer methods, will be discussed.
