ABSTRACT

This chapter examines the mutagenicity of the extractable organic material associated with inhalable particles at the airbourne toxic element and organic substance urban and rural sites over a two-year period. It evaluates seasonal variations in mutagenic activity, and attempts to relate mutagenic activity to some aspects of chemical composition. These data may be used for future epidemiological studies on the effects of air pollution on human health. In assessing potential health impacts associated with airborne particulate matter, the size of the particles collected is a crucial factor. In addition, the mutagenicity data on ambient air in New Jersey will be essential in evaluating the results of future site-specific studies on local air pollution sources in the state, and in examining long-term trends in ambient air quality. The standard Ames Salmonella reverse mutation plate incorporation assay was initially conducted using bacterial strains TA98, TA100, TA1535, TA1537, and TA1538.