ABSTRACT
Enterocytozoon bieneusi is a human-pathogenic species of the genus Enterocytozoon, which also includes another species affecting shrimps. E. bieneusi infection in individuals with HIV/AIDS, malnutritional children, and the recipients of immunosuppressive therapy often presents as acute or chronic diarrhea, abdominal pain, cholecystitis, weight loss, wasting syndrome, and occasional respiratory symptoms. Prevention of human E. bieneusi infection focuses on avoidance of contaminated water/food, filtration of water supply, and maintenance of hygienic conditions. Nucleotide sequences amplified from E. bieneusi isolates are first verified and then analyzed using relevant softwares to determine their genotypes and multilocus genotypes (MLG) and to reveal phylogenetic relationship and other population genetic details. E. bieneusi is an obligate intracellular parasite armed with polar tube and other devices that facilitate its interaction with and entry into the host cell, utilization of host cell machineries for its own growth and replication, and evasion of host immune responses during infection processes.
