ABSTRACT
Heterocycles belong to one of the most significant and fascinating classes of organic compounds because of their ability to act as both biomimetics and reactive pharmacophores. Flavonoids are a group of yellow-colored pigments and belong to a class of biologically important oxygen heterocycles. This chapter describes microwave-assisted syntheses and functionalization of diverse six-membered oxygen heterocycles. It provides an overall view of the microwave-assisted synthesis and functionalization of a variety of six-membered oxygen heterocycles. Among reported protocols, microwave-assisted organic synthesis has drawn considerable attention. The use of microwave irradiations in organic synthesis was first reported by R. Gedye and coworkers in the year 1986, which were found to be more beneficial than the conventional methods. Pyrans are six-membered oxygen heterocycles with a molecular formula C5H6O. The molecules occupy a unique place in pharmaceutical chemistry as they possess anticancer and antihypertensive activities.
