ABSTRACT
Primary hyperhidrosis (PH) is a relatively common chronic condition that causes excessive sweating in various parts of the body. It is caused by hyperreactivity of the sympathetic system resulting in excessive stimulation of the eccrine sweat glands. Primary palmar hyperhidrosis (PPH) is the most common variant of PH but is of unknown etiology. Clinical manifestations of PPH include wet and cold palms accompanied by change of color from pale to blush. They usually appear before the third decade of life, often during childhood and adolescence. Various medical treatment options are available and include topical agents, systemic anticholinergic medications, and local therapy. Compensatory sweating particularly of the trunk is very common in both adults and children but seems to be tolerated better by children than adults. With the emergence of video-assisted technology it has become the standard surgical approach and is the only permanent cure for both PPH and axillary hyperhidrosis.
