ABSTRACT
Pathologists in the international collaboration have established a new histopathological consensus classification for pediatric liver tumors. Concomitantly there have been advances in chemotherapy options, an increased rate of successful surgical resection for large bulky tumors, and progress in identifying biologic markers that portend increased or decreased risk. Complete surgical resection remains a cornerstone of successful outcomes and modern liver resection requires a fundamental understanding of liver anatomy, sophisticated radiographic imaging, thorough knowledge of disease pathophysiology and treatment protocols, and refined surgical techniques, all performed within the support network of a multidisciplinary liver team. The multidisciplinary treatment protocol will usually recommend the timing and type of surgical resection based upon the protocols surgical resection guidelines. Resection versus observation of the hepatic adenomas may often depend upon the genetic analysis of a percutaneous biopsy, or the presence of a known germline mutation.
