ABSTRACT
Quantifying Agonists and Antagonists 31
Experimental E/[A] curves are characterized by three parameters, a, [A]50, and m. Using Eq. (2), these experimental parameters can be written in terms of operational model parameters. This is illustrated below for the case where n = 1; that is, when E/[A] curves are founded to be hyperbolic (a relatively common experimental finding).
