ABSTRACT
MANIFESTATIONS OF MYASTHENIA GRAVIS Symptoms and Course Myasthenia gravis (MG) is a chronic disease characterized by weakness and abnormal fatigability of any or all of the skeletal muscles. In 14% of patients the disease remains clinically limited to the extraocular muscles and orbiculares oculi, with ptosis and/or diplopia, while in 86% it becomes generalized-in 87% of these within a year after onset, and in 94% within 3 years (1). In patients with generalized MG, weakness and fatigability of muscles of the eyes, face, neck, trunk, and limbs occur, and in nearly half the patients there are episodes of difficulty swallowing, chewing, speaking, coughing, and, less often, breathing.
