ABSTRACT

Introduction............................................................................................................113 The Gene Causing Fragile X:

FMR1

....................................................................114 Triplet Repeat Expansion in Fragile X .................................................................115 FMRP: The Protein Product of the Disease Gene in Fragile X Syndrome.........116 FMRP and the Neuronal Phenotype in Fragile X Syndrome...............................117 Fragile X Therapeutics ..........................................................................................120 Fragile X and Autism ............................................................................................121 Etiology of Autism ................................................................................................121 Finding the Disease-Causing Gene: Insight from Fragile X................................122 References..............................................................................................................123

Cognition