ABSTRACT
As many tissues in the body have elastomeric properties, successful replacement or tissue engineering of these tissues will require the development of compliant biodegradable elastomeric scaffolds that can sustain and recover from multiple deformations without irritation to the surrounding tissue. The development of elastomeric scaffolds is desirable because mechanical conditioning regimens have been shown to promote improved tissue formation and would allow gradual stress transfer from the degrading synthetic matrix to the newly formed tissue. J. Wang and coworkers first reported the use of the monomers as a novel elastomeric material for potential application in soft tissue engineering in 2002. Polyorganophosphazenes are a class of polymers of great potential for biomedical applications and biomaterials. The copolymerizations of PCL with polylactide or PGL can produce a novel material which will overcome the drawbacks of every single constituent, such as to provide better control over the degradation and mechanical properties without sacrificing biocompatibility.
