ABSTRACT
Taxonomy ....................................................................................................................................... 243 Neisseria gonorrhoeae ................................................................................................................... 243
Laboratory Diagnosis .........................................................................................................244 Gonococcal Disease............................................................................................................246 Meningococcal Disease ...................................................................................................... 247
Diagnosis .................................................................................................................. 247 Chemotherapy and Prophylaxis ............................................................................... 247
Laboratory Safety ...............................................................................................................248 References ......................................................................................................................................248
Bergey’s Manual of Systematic Bacteriology denes the family of Neisseriaceae as consisting of two separate rRNA superfamilies that have no level of relatedness. The true Neisseriaceae and two Kingella ssp. belong to the β-subclass of Proteobacteria. False Neisseria, Moraxella, Branhamella, and Acinetobacter genera belong to the γ-subclass of the Proteobacteria, and are removed from the family of Neisseriaceae. In addition, genetic studies have shown that Eikenella, Simonsiella, Alyseilla EF-4a, EF-4b, M-5, and M-6 (CDC groups) are related to the true Neisseriaceae and two Kinegella ssp. The present classication of the family of Neisseriaceae is Neisseria, Kingella, Eikenella, Simonsiella Alyseilla EF-4a, EF-4b, M-5 and M-6. Neisseria gonorrhoeae and N. meningitidis will be the only species discussed in this chapter because of pathogenicity in man. Species of the genus Neisseria found in the humans and animals inhabiting mucous membranes are listed in Table 19.1.
