ABSTRACT

The subject of systems biology encompasses, on the one hand, any biological systems, the characteristics of which can be quantitatively measured, and, on the other hand, the mathematical models that mimic the behavior of these biological systems. Systems biology primarily intends to construct a model which is the most closely related to the biological system under study and to reveal thereby new regulatory and dynamic properties as well as structure-mechanism relationships of this system. The criterion of adequacy of the mathematical model to the relevant biological system is the quality of simulation of all possible experimental data obtained for this biological object.