ABSTRACT

The experimentalist is often faced with the challenge of selectively separating a desired compound from a mixture and molecularly imprinted polymers (MIPs) can be instrumental in achieving such substrate selective separations. Polymers have been imprinted using organic molecules [1,2], metal ions [3^5], and large biomolecules such as proteins and DNA [6,7]. These di¡erent substrate types often require di¡erent strategies for optimal imprinting and recognition. However, most studies on molecular imprinting to date have focused on organic molecules, providing most of what is known about selectivity in MIPs.Therefore, treatment in this tutorial will correspondingly focus on imprinting small organic molecules. The category of organic molecule substrates can be further divided into:

1. enantiomeric organic molecules; 2. isomeric organic compounds; 3. different organic compounds.