ABSTRACT

Introduction .............................................................................................................41 Polyphenols in Grapes and Wine.............................................................................42 Polyphenols Metabolism .........................................................................................43 Role of Flavonoids in Cardiovascular Disease ........................................................44 Effects on Cholesterol .............................................................................................45 Antioxident Properties of Wine ...............................................................................46 LDL Oxidation ........................................................................................................47 Effects on Hemostasis .............................................................................................48 Nitric Oxide-Related Effects ...................................................................................50 Potential Adverse Effects of Polyphenols................................................................50 Conclusions .............................................................................................................51 Acknowledgment.....................................................................................................53 References ...............................................................................................................53

INTRODUCTION