ABSTRACT

Alcohol (ethanol) is directly hepatotoxic, as illustrated by epidemiologic data such as (1) the correlation between annual per capita alcohol consumption and the mortality from cirrhosis, or (2) the association of the relative risk for cirrhosis to daily alcohol consumption. The risk for cirrhosis appears to increase markedly above a threshold level of daily alcohol intake (80 g per day in men and 40 to 60 g per day in women).