ABSTRACT
The treatment of amyloidosis was primarily supportive. Specific criteria for recognizing organ involvement and defining response were of little benefit and minimal utility. Specific criteria for recognizing organ involvement and defining response were of little benefit and minimal utility. Deposits of amyloid have been shown by SAP scanning to be in dynamic equilibrium. Dissolution of amyloid deposits is possible if the production of the precursor light chain can be reduced. Each institution has its own specific criteria for evaluating the number of organs involved with amyloid and defining what constitutes a response. Defining organ involvement and response criteria for amyloidosis has always been challenging. The mission of the 13 members of the consensus panel was to define criteria that could be used worldwide by physicians who treat patients with this disease and to permit uniform reporting criteria of treatment-related outcomes.
