ABSTRACT
AA amyloidosis is sometimes seen in longstanding arthritis. Scintigraphy with I labelled serum amyloid P component (SAP) may be helpful to detect amyloidosis in patients suspected to have amyloidosis. Visual assessment of SAP scans in patients with amyloidosis at different time intervals after administration of the tracer in order to obtain the optimum time interval for scanning. Scans were made 0.5, 4, 24, and 48 hours after administration of the tracer and scored visually by two blinded investigators. Scans of controls were used to obtain guidelines for maximum normal uptake. The optimum time interval for making a scan was studied. Guidelines were formulated and used in a step-wise visual assessment of scans of patients with amyloidosis. The optimum time interval for the scan was 24 hours after injection of the tracer. The scan was useful in identifying patients with AL and AA amyloidosis. Intensity and time of uptake differed among organs.
