ABSTRACT
I. Introduction ...........................................................................................................................107 II. AECA in Primary Vasculitis .................................................................................................107 III. AECA in Secondary Vasculitis .............................................................................................108 IV. Assays for AECA Detection.................................................................................................109 V. Cell and Antigen Specificity .................................................................................................110 VI. The Pathogenic Role of AECA ............................................................................................111 References ......................................................................................................................................113
The endothelial cell (EC) surface is now considered a dynamic, heterogeneous organ that possesses synthetic, secretory, metabolic, and immunologic functions. Endothelial cells directly and indirectly play key roles in the development of vessel inflammatory injury associated with several vascular disorders.
