ABSTRACT

I. Introduction ...........................................................................................................................563 II. Treatment of Venous Thrombosis .........................................................................................563 III. Treatment of Arterial Thromboembolism.............................................................................565 IV. Bleeding Complications Associated with Anticoagulant Treatment....................................566 V. Monitoring Anticoagulants in the Presence of a Lupus Anticoagulant ...............................567 References ......................................................................................................................................568

The optimal treatment of vascular thrombosis in patients who have antiphospholipid antibodies has proven to be a challenge. The diversity of the thromboses — venous, arterial, and microvascular — suggests that multiple pathogenic mechanisms are involved.