ABSTRACT

Artificial Membrane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .323 15.4 The Future of Biomimetic Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . . .324 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325

In the biomimetic approach, we analyze biological functions and develop artificial systems that simulate or regenerate them. Most biological functions result from highly sophisticated sequential events where specific recognitions and reactions are driven by multiple weak dynamics such as electrostatic interaction, hydrogen bonding, and hydrophobic interaction. Supermolecules such as host-guest systems can sometimes be regarded as good models of biological receptor-substrate systems. A well designed host might induce the chemical reaction of a bound guest molecule and serve as an effective mimic of an enzyme function. The first part of this chapter discusses several examples of artificial receptors and artificial enzymes as individual biomimetic elements.