ABSTRACT
Mitsuhiro Kawata, Mayumi Nishi, Ken-ichi Matsuda, Hiroshi Ogawa, Ikuo Ochiai, and Maki Yoshida
CONTENTS
I. Introduction................................................................................. 273 II. Localization of Corticosteroid Receptors in the Brain ............ 274
III. Subcellular Localization of Corticosteroid Receptors.............. 275 IV. Localization of Sex Steroid Hormone Receptors
in the Brain.................................................................................. 277 V. Subcellular Localization of Sex Steroid Hormone
Receptors ..................................................................................... 279 VI. Localization of Coactivators in the Brain ................................. 280
VII. Subcellular Localization of Nuclear Receptor Coactivators and Dynamic Intracellular Trafficking of Steroid Hormone Receptors .................................................. 281
References ............................................................................................. 282
The brain is a target organ for circulating steroid hormones secreted from peripheral endocrine tissues. Steroid hormones regulate many important functions not only during development, but also into adulthood. Due to their chemical property of lipid solubility, steroid hormones cross the blood-brain barrier and function on neuronal cells through their receptors.