ABSTRACT

CONTENTS 38.1 Introduction .........................................................................................................801 38.2 Analytical Methods ............................................................................................ 802

38.2.1 Screening Methods ............................................................................... 803 38.2.2 Con rmatory Methods ......................................................................... 804

38.2.2.1 Sample Preparation .............................................................. 804 38.2.2.2 Liquid Chromatography and Ultraperformance Liquid

Chromatography Separation ................................................ 805 38.2.2.3 Mass Spectrometry ...............................................................810 38.2.2.4 LC-MS Con rmatory Criteria .............................................811