ABSTRACT

Contents 6.1 The epigenetic language ....................................................................... 127 6.2 Epigenetic deregulation and cancer ................................................... 130

6.2.1 DNA methylation in cancers .................................................... 130 6.2.2 Histone acetylation and cancers .............................................. 131

6.3 Epigenetic deregulation, chronic inflammation, and natural therapeutics .............................................................................. 134 6.3.1 Chronic inflammation: The cradle of cancer ......................... 134 6.3.2 Targeting HAT and HDAC enzymes with dietary

and other natural compounds ................................................. 136 6.4 Conclusions .............................................................................................141 References .........................................................................................................141