In this chapter we examine the phylogenetic relationships of flies in the tephritid subtribe Carpomyina. Our primary goal is to establish the current state of knowledge by consolidating information from various phylogenies that have been generated using morphology (Bush 1966; Norrbom 1994; 1997; Jenkins 1996), allozymes (Berlocher and Bush 1982; Berlocher et al. 1993) and DNA sequences (McPheron and Han 1997; Smith and Bush 1997).